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CoQ10

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$33.00

Quick Overview

Enhanced Bioactivity CoQ10
Promotes Improved Cardio Function

Ubiquinol is the most superior form of CoQ10 on the market.

Kaneka Corporation created and manufactured the first ever developed ubiquinol form of CoQ10 and AlignLife has secured this advanced form to utilize in "AlignLife CoQ10" to maximize your energy production*, cardiovascular health*, gum health* and longevity*.

To date, every clinical trial has shown Ubiquinol to provide vastly superior 
results to that of conventional CoQ10.

If you are currently taking conventional CoQ10 in the ubiquinone form (check your label) you are ingesting the inferior form of the nutrient. Ubiquinol is the superior form of CoQ10 due to its enhanced absorption and utilization in the body.

Ubiquionol is required for 95% of your cellular energy production due to its ability to protect the integrity of the mitochondria (the energy producing part of the cell).

Ubiquionol helps to maintain cardiovascular health* by protecting the arterial system of the body. If the essential levels of CoQ10 are allowed to decline, and the body's vital organs cannot meet their energy requirements, the results are deteriorated health and disease, fatigue, and most commonly, impaired heart muscle function. CoQ10 is an important nutrient for the heart.

Preliminary studies have shown that Ubiquinol levels are significantly diminished by aging and therefore increasing levels may have an effect on objective markers for aging (cardiovascular compromise and fatigue).

Individuals with bleeding gums or periodontal disease can benefit from the ubiquinol form of CoQ10. By helping cells create the energy necessary for healing and repair, CoQ10 supplementation can effectively help manage gum disease*.


The following drugs may cause a deficiency of CoQ10 and therefore it is recommended to supplement with CoQ10:
Atorvastatin, Doxorubicin, Fluvastatin, Gemfibrozil, HMG-CoA Reductase Inhibitors (Statins), Lovastatin, Perphenazine, Pravastatin, Propranolol, Simvastatin, Thioridazine, Timolol, and Tricyclic Antidepressants.


 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

 

SUPPLEMENT FACTS

Serving Size: 3 Capsule

 

Servings per Container: 30 

 

 

 

 

AMOUNT PER SERVING
% Daily Value

 

 

 

 

Ubiquinol (KanekaQH)

100

mg

† Daily Value not established

Other Ingredients: Pure Olive Oil, Gelatin, Vegetable Glycerin.
Contains <2% of: Ascorbyl Palmitate, Natural Carmel Color, Soy Lecithin, Titanium Dioxide Color
Sell Ingredients: Gelatin, Vegetable Glycerin, Natural Carmel Color, Titanium Dioxide Color, Purified Water 

 

 

 

 

           

All AlignLife® Formulas Meet or Exceed cGMP Quality Standards.

Suggested Use:  As a dietary supplement, take 3 capsules twice daily with meals.


Congestive Heart Failure - 300mg a day for 2 weeks, then 200mg a day

Heart Attack300-600mg a day for one month, then 200mg a day

High Blood Pressure60-200mg a day

Taking Statin Drugs200-400mg a day
 

Precautions:

There are no known negative interactions with medications or other nutrients at this time.

Does Not Contain:

Wheat, gluten, dairy, corn, yeast, artificial sweeteners and flavors. (Contains soy.)

Disclosure:

Keep container tightly closed. Store at room temperature. Keep out of reach of children. This product was sealed for your protection. Do not use if outer logoed neck seal or inner-seal is missing or damaged.Consult your physician before taking dietary supplements if you are pregnant or nursing.As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion.

 

CoQ10 Research Collection

1. Aberg F, Appelkvist EL, Dallner G, Ernster L. Distribution and redox state of ubiquinones in rat and human tissues. Arch Biochem Biophys. 1992 Jun;295(2):230-4.

2. Alleva R, Tomasetti M, Bompadre S, Littarru GP. Oxidation of LDL and their subfractions: kinetic aspects and CoQ10 content. Mol Aspects Med. 1997;18 Suppl:S105-12.

3. Beamer WM and Deamer DW. Energy from Chemical Bonds: The aerobic mode. In: The World of the Cell, 2nd Ed., The Benjamin Cummings Publishing Company, Inc, Redwood City , Caluifornia, 1991, pps. 275-313.

4. Bhagavan HN, Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007 Jun;7 Suppl:S78-88.

5. Ernster L, Forsmark-Andrée P. Ubiquinol: an endogenous antioxidant in aerobic organisms. Clin Investig. 1993;71(8 Suppl):S60-5.

6. Evans M, Baisley J, Barss S, Guthrie N. A randomized, double-blind trial on the bioavailability of two CoQ10 formulations. Journal of Functional Foods. 2009. 1: 65-73.

7. Forsmark-Andrée P, Ernster L. Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation. Mol Aspects Med. 1994;15 Suppl:s73-81.

8. Forsmark-Andrée P, Lee CP, Dallner G, Ernster L. Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles. Free Radic Biol Med. 1997;22(3):391-400.

9. Frei B, Kim MC, Ames BN.Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83.

10. Halliwell B, Hu ML, Louie S, Duvall TR, Tarkington BK, Motchnik P, Cross CE. Interaction of nitrogen dioxide with human plasma. Antioxidant depletion and oxidative damage. FEBS Lett. 1992 Nov 16;313(1):62-6.

11. Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M. Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol. 2007 Feb;47(1):19-28.

12. Isobe C, Abe T, Terayama Y. Increase in the oxidized/total coenzyme Q10 Q-10 ratio in the cerebrospinal fluid of Alzheimer’s disease patients. Dement Geriatr Cogn Disord. 2009;28(5):449-54. Langsjoen PH, Langsjoen AM. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors. 2008;32(1-4):119-28.

13. Lim SC, Tan HH, Goh SK, Subramaniam T, Sum CF, Tan IK, Lee BL, Ong CN. Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q(10). Diabet Med. 2006 Dec;23(12):1344-9.

14. Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007 Sep;37(1):31-7.

15. Maguire JJ, Wilson DS, Packer L. Mitochondrial electron transport-linked tocopheroxyl radical reduction. J Biol Chem. 1989 Dec 25;264(36):21462-5.

16. Martini FH. Muscle tissue. In: Fundamentals of Anatomy and Physiology, Prentice Hall, Inc, Upper Saddle River, New Jersey, 1999-2000 online version, accessed on June 6, 2011; http://cwx. prenhall.com/bookbind/pubbooks/martinidemo/chapter10/medialib/ CH10/html/ch10_5_2.html.

17. Miles MV, Horn P, Milesc L, Tanga P, Steele P, DeGrauwa T. Bioequivalence of coenzyme Q10 from over-the-counter supplements. Nutr Res. 2002:22(8):919-929.

18. Miles MV, Patterson BJ, Chalfonte-Evans ML, Horn PS, Hickey FJ, Schapiro MB, Steele PE, Tang PH, Hotze SL. Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21. Pediatr Neurol. 2007 Dec;37(6):398-403.

19. Mohr D, Bowry VW, Stocker R. Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta. 1992 Jun 26;1126(3):247-54.

20. Saito Y, Fukuhara A, Nishio K, Hayakawa M, Ogawa Y, Sakamoto H, Fujii K, Yoshida Y, Niki E. Characterization of cellular uptake and distribution of coenzyme Q10 and vitamin E in PC12 cells. J Nutr Biochem. 2009 May;20(5):350-7.

21. Shoko D, Fujii K, Kurihara T. The effect of the reduced form of coenzyme Q10 (Ubiquinol, Kaneka QH™ ) on QOL improvement in the elderly. J Clin Therap Med 2008; 24:233-238.

22. Schmelzer C, Niklowitz P, Okun JG, Haas D, Menke T, Döring F. Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans. IUBMB Life. 2011 Jan;63(1):42-8.

23. Sohmiya M, Tanaka M, Suzuki Y, Tanino Y, Okamoto K, Yamamoto Y. An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. J Neurol Sci. 2005 Jan 15;228(1):49-53.

24. Stocker R, Bowry VW, Frei B. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci USA. 1991 Mar 1;88(5):1646-50.

25. Tang PH, Miles MV, DeGrauw A, Hershey A, Pesce A. HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma. Clin Chem. 2001 Feb;47(2):256-65.

26. Tomasetti M, Littarru GP, Stocker R, Alleva R. Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes. Free Radic Biol Med. 1999 Nov;27(9-10):1027-32.

27. Tomasetti M, Alleva R, Borghi B, Collins AR. In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage. FASEB J. 2001 Jun;15(8):1425-7.

28. Wada H, Goto H, Hagiwara S, Yamamoto Y. Redox status of coenzyme Q10 is associated with chronological age. J Am Geriatr Soc. 2007 Jul;55(7):1141-2.

29. Yamamoto Y, Yamashita S. Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion. Biofactors. 1999;9(2-4):241-6.

30. Yamashita S, Yamamoto Y. Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress. Anal Biochem. 1997 Jul 15;250(1):66-73.

31. Yan J, Fujii K, Yao J, Kishida H, Hosoe K, Sawashita J, Takeda T, Mori M, Higuchi K. Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice. Exp Gerontol. 2006 Feb;41(2):130-40.


* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using this product.